how well your cancer responds to treatment.the hormone receptor (HR) or human epidermal growth factor receptor 2 (HER2) status of your cancer.For example, the survival rates reported by the ACS rely on data from the Surveillance, Epidemiology, and End Results (SEER) database, which is managed by the NCI.īecause survival rates use data from a large sample of women, they do not account for individual factors, such as: However, there’s some important things to know about these numbers.īreast cancer survival rates are based on data on the outcomes of a large number of women with breast cancer. Survival rates can be useful for giving you an overall idea of your cancer prognosis. This varies from person to person, and there are a number of factors that affect prognosis, including a person’s age and the type, grade, and size of the cancer.īelow, we’ll explore what we know about the prognosis of breast cancer based on several factors, including the extent of the cancer, your age, and race. When you receive a breast cancer diagnosis, your doctor will estimate the likely course and outcome of your condition. However, due to improved detection and treatment, deaths have dropped 41 percent from 1989 to 2018, according to the ACS. The National Cancer Institute (NCI) estimates that about 281,550 women will be diagnosed with breast cancer in 2021, and about 43,600 will die of the disease. Breast cancer incidence has been slowly rising in the United States, where it has increased by 0.5 percent each year from 2008 to 2017. The ACS predicts that 13 percent of women in the United States will develop breast cancer in their lifetime. Globally, about 2.3 million new cases were reported in 2020, accounting for 11.7 percent of new cancer diagnoses worldwide, according to the American Cancer Society (ACS). Early detection is key to a better outlook.īreast cancer is the most common form of cancer affecting women and is also now the most commonly diagnosed cancer worldwide. However, 5-year survival rates are as high as 93% to 98% when cancer is diagnosed before it spreads beyond the breast. Understanding more about the chemical and genetic makeup of your cancer may help doctors choose the most effective treatment for your specific cancer.Factors such as age, race, and gender can all affect your outlook. Basal-like breast cancers are likely to benefit from chemotherapy. This type, which is also called triple-negative breast cancer, includes tumors that are ER negative, PR negative and HER2 negative. HER2 breast cancers are likely to benefit from chemotherapy and treatment targeted to HER2. This type includes tumors that are ER negative and PR negative, but HER2 positive. Luminal B breast cancers are likely to benefit from chemotherapy and may benefit from hormone therapy and treatment targeted to HER2. This type includes tumors that are ER positive, PR negative and HER2 positive. Luminal A breast cancers are likely to benefit from hormone therapy and may also benefit from chemotherapy. This group includes tumors that are ER positive and PR positive, but negative for HER2. These groups help guide decisions about which treatments are best. Ask your doctor whether this type of test might be helpful in your case.ĭoctors are increasingly using genetic information about breast cancer cells to categorize breast cancers. Tests that analyze the genetic makeup of breast cancers are available but aren't recommended in all situations. That way, women with relatively low-risk breast cancers may avoid aggressive treatments. Doctors hope this information can be used to predict which cancers will spread and which may need aggressive treatments. Researchers are studying ways to interpret the genetic makeup of tumor cells. Targeted therapy drugs are available to shut down the HER2 protein, thus slowing the growth and killing these cancer cells. Cancer cells that have too many copies of the HER2 gene (HER2-positive cancers) produce too much of the growth-promoting protein called HER2. A sample of your tumor tissue from a biopsy procedure may be tested in a laboratory to look for:
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